This opportunity aims to support research on innovative screening approaches and therapies for screenable disorders in newborns. The goal is to develop novel screening tests and therapeutic interventions for conditions that can be identified through newborn screening. The research should focus on "high priority" genetic conditions where screening may be possible in the near future. The funding will support projects that demonstrate the benefits of early intervention or treatment. • The research should be relevant to the development of novel screening approaches and/or therapeutic interventions for potentially fatal or disabling conditions. • The funding will support projects that demonstrate the benefits of early intervention or treatment. • The research should focus on "high priority" genetic conditions where screening may be possible in the near future. • The funding will support projects that develop novel screening tests and therapeutic interventions for conditions that can be identified through newborn screening.