The National Institute of Environmental Health Sciences (NIEHS) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the NIEHS Worker Training Program’s SBIR E-Learning for HAZMAT and Emergency Response. The purpose of this NOFO is to encourage Small Business Innovation Research (SBIR) grant applications from small business concerns that propose to further the development of Technology-Enhanced Training Products for the health and safety training of hazardous materials workers. The products must complement the goals and objectives of the Worker Training Program (WTP), which aims to prevent work-related harm by training workers in how best to protect themselves and their communities from exposure to hazardous materials. Key points to consider: • The NIEHS WTP is authorized by the Superfund Amendments and Reauthorization Act of 1986 (SARA), Section 126(g) • The program provides support for the development of Technology-Enhanced Training Products, including online training, mobile device training, augmented reality (AR), virtual reality (VR), and serious gaming • The funding opportunity will solicit R43/R44 SBIR grant applications • The estimated funding for this initiative is $688,000, with an estimated 6 awards to be made • The estimated project start date is June 1, 2026