This funding opportunity, titled "Translation and Diffusion," aims to encourage the scientific study of theories, frameworks, and models for the translation and diffusion of knowledge, especially between fields and across contexts and levels-of-analysis, in PreK-12 STEM classroom practice. The solicitation invites four types of proposals: Research on Translation or Diffusion, Proof-of-Concept Research, Synthesis, and Conference/Workshop proposals. The goal is to advance or move specific practice, research, or scientific discovery in STEM education reciprocally along the research-practice continuum. • The first goal of this funding opportunity is to encourage the scientific study of theories, frameworks, and models for the translation and diffusion of knowledge. • The second goal is to advance or move specific practice, research or scientific discovery in STEM education reciprocally along the research-practice continuum. • The solicitation invites four types of proposals: Research on Translation or Diffusion, Proof-of-Concept Research, Synthesis, and Conference/Workshop proposals. • Proposals may only be submitted by eligible organizations, including U.S.-based commercial organizations, non-profit organizations, institutions of higher education, and tribal nations. • The estimated funding for this opportunity is $7,000,000.