The National Institutes of Health (NIH) is seeking applications for the NIMH Exploratory/Developmental Research Grant (R21 Clinical Trial Not Allowed). This grant program supports exploratory and high-risk research projects that fall within the NIMH mission by providing support for the early and conceptual stages of these projects. The studies may involve considerable risk but may lead to a breakthrough or to the development of novel techniques, agents, methods, measures, models, or strategies, or to the generation of pilot or feasibility data. The key aspects of this opportunity include: • Support for exploratory and high-risk research projects • Focus on early and conceptual stages of projects • Potential for breakthroughs or development of novel techniques • Eligibility for various types of organizations, including institutions of higher education, non-profits, and small businesses • Award ceiling of $275,000 • Project duration of 1-2 years (although not explicitly stated)