The National Institutes of Health (NIH) is seeking applications for the Trailblazer Award, which supports New and Early Stage Investigators pursuing research programs that integrate engineering and the physical sciences with the life and/or biomedical sciences. The award is designed to support exploratory, developmental, proof of concept, or high risk-high impact research. Applicants are not required to provide preliminary data, but if available, minimal preliminary data are allowed. The award is intended to support research that is innovative and has the potential to lead to significant advances in the field. • The award is open to New and Early Stage Investigators, as defined by the NIH. • The research must integrate engineering and the physical sciences with the life and/or biomedical sciences. • Preliminary data are not required, but if available, minimal preliminary data are allowed. • The award is intended to support exploratory, developmental, proof of concept, or high risk-high impact research. • The application must be submitted electronically through the NIH website.