NIH Directors Transformative Research Awards (R01 Clinical Trial Optional)

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Title:  

NIH Directors Transformative Research Awards (R01 Clinical Trial Optional)

Agency:  

U.S. National Institutes of Health

State:  

United States of America

NAICS Code:  

541710

Industry:  

Healthcare and Medical Services

Solicitation Type:  

Grants Notice

Solicitation ID:  

RFA-RM-25-003

Open Date:  

5/12/2025

Close Date:  

9/3/2025

Projected Award Date:  

9/18/2026

Last Updated:  

Description:
The NIH Directors Transformative Research Award Program supports individual scientists or groups of scientists proposing bold, groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. The program is part of the High-Risk, High-Reward Research program and will utilize the R01 activity code. • Applications are not being solicited at this time, but notice is being provided to allow potential applicants sufficient time to develop meaningful and responsive projects. • Investigators of exceptional creativity with a high-risk, high-impact proposal are encouraged to begin to consider applying for this new NOFO. • Preliminary data and detailed experimental plans are not requested or required. • The estimated funding for this program is $8,000,000, and the estimated number of awards is 7.
Attached Files:

Please visit the bid source via the “Link to Bid Source” button below for documentation.

Contact Information:

Patricia Labosky, Ph.D.(Office of the Director (OD))

Transformative_Awards@mail.nih.gov

(301) 594-4863

Budget Estimate (AI):

$500,000 – $2,000,000

Based on the estimated funding for this program, which is $8,000,000, and the estimated number of awards, which is 7, the budget for each award can be estimated to be around $1,142,857. However, this is just an estimate and the actual budget may vary. The budget may be influenced by factors such as the quality of the proposals, the availability of funds, and the priorities of the National Institutes of Health.

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