Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R33 Clinical Trial Required)

The National Institutes of Health (NIH) is seeking applications for the development of psychosocial therapeutic and preventive interventions for mental disorders. This initiative aims to support pilot research that develops and tests novel psychosocial interventions and/or targets, with the goal of speeding the translation of emergent research into preventative or therapeutic interventions. The funding will provide up to three years of support to replicate target engagement from prior studies and to test the association between target engagement and change in clinical outcome(s). Key aspects of this opportunity include: • Development of novel psychosocial interventions for mental disorders • Testing of preventative or therapeutic interventions • Replication of target engagement from prior studies • Association between target engagement and change in clinical outcome(s) • Up to three years of funding support • Applications from various eligible entities, including institutions of higher education, non-profits, and small businesses, are encouraged.