Limited Competition: Intellectual and Developmental Disabilities Research Centers 2027 (P50 Clinical Trial Optional)

The purpose of this Notice of Funding Opportunity (NOFO) is to seek applications for the Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Centers (IDDRCs). This NOFO invites applications for research center grants designed to advance the diagnosis, prevention, treatment, and amelioration of intellectual and developmental disabilities (IDD) and is limited to currently funded IDDRCs under RFA-HD-20-016 or RFA-HD-21-009. The IDDRCs will promote highly collaborative, basic, translational, and clinical research in IDD. Some key points of this opportunity include: * The duration of these Centers will be 3 years in total. * Collaborative investigations combining expertise in translational science, biomarker assessment, outcome measure development, tool validation, bioinformatics, and therapeutic development will be encouraged. * Funds for the majority of outside research projects using these core facilities come from independent sources including Federal, State, and private organizations. * The Center should include plans for outreach, engagement, and dissemination to the community, including persons with lived experience (PWLE) of disabilities.