R3PEATS Multi-Team Triangulation: Collaborative Cross-Method Approaches to Scientific Discovery (RM1)

The NIH Common Fund’s R3PEATS program seeks up to five multi‑team, cross‑method research projects that will address a single high‑impact biomedical question using complementary models, methods, or populations. Each award will require rigorous triangulation, built‑in replication, and analysis of biological variability to improve rigor and reproducibility. Projects are expected to be collaborative, involving distinct research teams that coordinate their efforts throughout the study lifecycle. Funding of $5,000,000 total (approximately $1 M per award) is anticipated, with awards expected to begin in July 2028. Applicants may include a broad range of entities—from universities and research institutes to non‑profits, tribal governments, and foreign institutions—provided they meet eligibility criteria. The solicitation does not list a specific submission deadline, pre‑bid meeting, or site visit, and the award date is projected for July 2028. • Supports coordinated, multi‑team biomedical research focused on reproducibility. • Up to five awards; total estimated funding $5 M (≈$1 M per award). • Open to a wide variety of eligible applicants (public, private, tribal, non‑U.S.). • No explicit submission deadline or pre‑bid meeting; forecast dates indicate posting 9/11/2026, award July 2028. • Emphasis on cross‑method triangulation, replication, and analysis of variability.