ARPA-H Emerging Health Innovators (EHI) Initiative

The Advanced Research Projects Agency for Health (ARPA‑H) is soliciting bold, early‑career‑focused research proposals across 16 defined “Topic Areas” that aim to transform biomedical, health, and community‑engaged science. The award will be structured as an Other‑Transaction Agreement with up to $1.05 M total funding (base $700 k + optional $350 k Director’s Award), paid on quarterly milestone completion. Eligible proposers must be U.S. institutions and the principal investigator must be ≤ 8 years post‑terminal degree. Proposals must first submit an anonymous solution summary (due 30 Oct 2026) and, if encouraged, a full technical & management proposal (due 10 Feb 2027). Key requirements include a single‑PI, U.S.‑based subcontractor cap of 30 % of total award, mandatory annual in‑person meeting and networking event, and compliance with human/animal‑subject, cybersecurity, and IP policies. • 16 distinct technical topics ranging from deep‑brain stimulation for sleep to implantable cancer‑adjuvant devices. • Funding limited to $700 k base plus optional $350 k third‑year award; all costs must be reasonable and within the 30 % subcontractor limit. • Early‑career PI eligibility (≤ 8 years after first terminal degree) and single‑PI, single‑topic submission rules.