The National Institute of Allergy and Infectious Diseases (NIAID) is seeking to establish a cooperative network to rapidly implement clinical trials for therapeutics, vaccines, biologics, diagnostics, and devices targeting infectious diseases. The network will consist of Clinical Trial Evaluation Units (CTEUs) and a Network Coordination Center (NCC). The initiative aims to support the evaluation of innovative concepts for advancing public health while mentoring the next generation of clinical trialists. Key aspects of the opportunity include: • The network will support clinical trials and studies for public health priorities, with a focus on emerging and chronic infections. • The CTEUs will provide the clinical infrastructure for implementing the clinical trials and studies. • The NCC will provide the administrative and organizational framework of the network, engaging with experts in the field to solicit and generate innovative concepts. • The initiative is supported by grant authorities under Sections 301 and 405 of the Public Health Service Act as amended.