Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required)

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated fully remotely delivered and conducted clinical trials to assess the efficacy or effectiveness of complementary and integrative health interventions in NCCIH-designated areas of high research priority. The key aspects of this opportunity include: • Remotely delivered and conducted clinical trials with no in-person contact between research staff and study participants • Utilization of mHealth tools or technologies • Justification for the remotely delivered approach and preliminary data on feasibility and safety • Evidence of the intervention's promise of clinical benefit • Requirement for a Plan for Enhancing Diverse Perspectives (PEDP) as part of the application