Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)

The National Institutes of Health (NIH) is seeking applications for research projects to evaluate the effectiveness of therapeutic and service delivery interventions for the post-acute management of mental health conditions. The purpose of this Notice of Funding Opportunity (NOFO) is to support effectiveness trials testing post-acute phase interventions that are statistically powered to provide a definitive answer regarding the study intervention's effectiveness. * The opportunity is open to various types of applicants, including private institutions of higher education, special district governments, and non-profits. * The funding instrument for this opportunity is a grant. * The expected application count is 100, and the expected application size is 0. * The opportunity is electronic and requires the use of the SF 424 (R&R) form. * The competition title for this opportunity is "Use for due dates on or after January 25, 2025". * The opportunity is not open to multi-project applications. * The opportunity has a grace period of 35 days.