Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)

The purpose of this notice of funding opportunity (NOFO) is to solicit applications for pilot projects to elucidate a role for understudied proteins in rare disease. Awards will support generation of preliminary data and/or tools around eligible understudied protein(s). A list of eligible proteins is provided and are members of druggable protein families that have a known association with a rare disease. This NOFO is intended to jumpstart research on understudied proteins that are associated with rare diseases and provide applicants with sufficient funding to perform basic biochemical and/or biological work to further the characterization of understudied proteins within the context of rare disease. • The award will support pilot projects to investigate understudied proteins associated with rare diseases. • The project aims to generate preliminary data and/or tools around eligible understudied protein(s). • A list of eligible proteins is provided, which are members of druggable protein families with a known association with a rare disease. • The funding will support basic biochemical and/or biological work to further the characterization of understudied proteins within the context of rare disease. • The award ceiling is $100,000.