Mind and Body Interventions to Restore Whole Person Health via Emotional Well-Being Mechanisms (R61/R33 Clinical Trial Required)

The National Center for Complementary and Integrative Health (NCCIH) is seeking applications for research on how mind and body interventions improve whole person health via emotional well-being. The initiative will support rigorous and well-powered mechanistic research studies with strong preliminary data to understand the relationships between mind and body interventions, mechanisms of emotional well-being, and whole person health. • The research should focus on mind and body interventions such as mindfulness meditation, yoga, acupuncture, massage, and other brain and/or body-based interventions. • The studies should examine the effects of mind and body interventions on innovative mechanisms of emotional well-being as the primary outcome, and the associated relationship with the Whole Person Health Index as a secondary outcome. • The funding will support an initial phase to establish feasibility benchmarks for the proposed mechanistic clinical trial(s), followed by a second phase to complete the full-scale trials contingent on successful completion of the initial phase milestones.