INCLUDE Project: Omics Phenotypes Related to Down Syndrome (X01 Clinical Trial Not Allowed)

The National Institutes of Health (NIH) is seeking applications for the INCLUDE Project, which aims to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications to submit samples to NIH INCLUDE Project-supported resources to generate a large volume of integrated genomic and multi-omics data. The resulting data, and associated clinical and phenotypic data, will become part of the INCLUDE Data Hub for sharing with the research community. • The project will focus on omics assays of existing biospecimens collected from individuals with Down syndrome and controls. • No funding will be provided directly to applicants under this NOFO. • Applicants are encouraged to propose omics assays of existing biospecimens. • The INCLUDE Data Hub will share the resulting data with the research community.