Description
This NIH Notice of Funding Opportunity (NOFO) solicits investigator‑initiated Program Project (P01) applications. A P01 supports a broadly based, multidisciplinary research program centered on a major scientific theme. Each application must include at least two research projects, an Administrative Core, and may include optional scientific cores. The award is a grant (not a contract) and can be “Clinical Trial Optional,” meaning applicants may propose a clinical trial component but are not required to. The opportunity is open to a wide range of eligible entities, including universities, non‑profits, for‑profit firms, state and tribal governments, and foreign institutions. Key dates: posting Oct 14 2026, application deadline May 25 2029, anticipated award July 1 2027. No cost‑sharing required. Applicants are encouraged to contact the participating NIH Institutes/Centers 60 days before the receipt date to discuss core requirements.
• Multidisciplinary P01 grant (minimum 2 research projects + Admin Core)
• Clinical‑trial optional component
• Open to many U.S. and non‑U.S. entities (public, private, nonprofit, tribal, etc.)
• No cost‑sharing required; award ceiling not specified (typically multi‑million)
• Application deadline May 25 2029; award expected July 2027
• Primary contact: Referral Officer, NIH ([email protected])