Enhancement and Expansion of ED-MOUD and Overdose Education and Naloxone Distribution Programs with Outcomes Analysis

The Mississippi State Department of Health (MSDH) is soliciting applications from qualified organizations to enhance, expand, and support an existing Emergency Department–based Medication for Opioid Use Disorder (ED-MOUD) program within a Mississippi academic medical center. The selected Subgrantee will support the initiation of MOUD in the emergency department, strengthen referral and linkage processes to specialty psychiatry and other appropriate providers for continued treatment and care, and expand an existing Emergency Department–based Overdose Education and Naloxone Distribution (OEND) program. Key activities include: • Strengthening initiation of MOUD within the emergency department and facilitating continuity of treatment • Improving screening and identification of individuals with substance use disorder (SUD) • Strengthening referral, navigation, and warm-handoff processes to specialty psychiatry and other appropriate services • Expanding overdose education and naloxone distribution among individuals at increased risk of experiencing or witnessing an overdose • Improving post-discharge follow-up and continuity of care • Evaluating program implementation, patient engagement, linkage and retention in care, naloxone distribution and utilization, and other applicable outcomes. The project aims to support evidence-based and data-informed approaches to strengthen early identification of substance use disorder, initiation of and linkage to treatment, harm reduction, overdose prevention, patient navigation, continuity of care, and evaluation of outcomes for individuals at risk for or experiencing SUD.