A Holistic Approach to Study Non-Addictive Natural Products for Pain Management

The National Institutes of Health (NIH) is seeking applications for a research project that aims to advance the understanding of non-addictive natural products for chronic pain management. The project should take a holistic approach, examining how these products influence pain through coordinated biological pathways across multiple organ systems. The research should also explore dose optimization and optimal intervention timing to maximize therapeutic outcomes. The goal of this project is to generate foundational insights that can inform future translational research and guide the development of safe, evidence-based, non-addictive strategies for pain management. • The project should focus on non-addictive natural products, including botanicals, dietary supplements, and other naturally derived compounds. • The research should take a holistic approach, examining the complex, multisystem actions of these products. • The project should explore dose optimization and optimal intervention timing to maximize therapeutic outcomes. • The research should generate foundational insights that can inform future translational research and guide the development of safe, evidence-based, non-addictive strategies for pain management.