The Missile Defense Agency (MDA) is seeking innovative concepts, technological innovations, prototype demonstrations, and scientific breakthroughs to enhance the robustness and effectiveness of the Missile Defense System. The MDA is interested in the rapid development of cutting-edge, disruptive technologies to revolutionize missile defense capabilities. The announcement includes topic areas such as Kinetic and Hypersonic Defense, Command and Control Battle Management, Integrated Non-Kinetic and Electronic Warfare, Disruptive Technologies, Space-based Sensors, Interceptors and Effectors, Digital Revolution, Radiation Effects, and International Missile Defense System Cooperation. • The MDA is seeking proposals that can provide innovative solutions to enhance the capabilities of current systems and achieve revolutionary leaps in far-term systems. • The announcement is open to all eligible offerors, and individual solicitations will specify the requirements for response. • The MDA reserves the right to award all, some, or none of the responses submitted to an individual solicitation. • The period of performance and funding availability will be specified in individual solicitations. • The MDA will protect all responses and proprietary information from unauthorized disclosure.