Pre-Clinical Models of Infectious Diseases

The National Institute of Allergy and Infectious Diseases (NIAID) is issuing a pre‑solicitation notice for an Indefinite Delivery Indefinite Quantity (IDIQ) contract to develop, refine, and evaluate pre‑clinical animal and animal‑replacement models for infectious disease research. The work includes creating new small‑animal, non‑human‑primate, and non‑traditional models, generating specialized reagents, and supporting regulatory submissions for candidate medical countermeasures such as vaccines, therapeutics, and diagnostics. Contractors may bid on one or more task areas and must have the capability to perform model development, model refinement, and product evaluation under Good Laboratory Practices and the FDA Animal Efficacy Rule. • Task Areas: Small‑animal models, Non‑human‑primate models, Animal‑replacement/non‑traditional models, Specialized reagent generation. • Scope: Model development, model refinement, efficacy testing, pharmacokinetics/pharmacodynamics, reagent production, and bridging studies. • Eligibility: Open to entities that can perform any of the listed task areas; collaborations/sub‑contracts are permissible but the prime contractor remains responsible for all deliverables.